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Structure-activity relationship of human glutaminyl cyclase inhibitors having an N-(5-methyl-1H-imidazol-1-yl) propyl thiourea template. Tran PT, Hoang VH, Thorat SA, Kim SE, Ann J, Chang YJ, Nam DW, Song H, Mook-Jung I, Lee J, Lee J. Bioorg Med Chem. 2013 Jul 1;21(13):3821-30. |
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Quantitative proteomic analysis of the hippocampus in the 5XFAD mouse model at early stages of Alzheimer's disease pathology. Hong I, Kang T, Yoo Y, Park R, Lee J, Lee S, Kim J, Song B, Kim SY, Moon M, Yun KN, Kim JY, Mook-Jung I, Park YM, Choi S. J Alzheimers Dis. 2013 Jan 1;36(2):321-34. |
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SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians. Miyashita A, Koike A, Jun G, Wang LS, Takahashi S, Matsubara E, Kawarabayashi T, Shoji M,Tomita N, Arai H, Asada T, Harigaya Y, Ikeda M, Amari M, Hanyu H, Higuchi S, Ikeuchi T,Nishizawa M, Suga M, Kawase Y, Akatsu H, Kosaka K, Yamamoto T, Imagawa M, Hamaguchi T, Yamada M, Moriaha T, Takeda M, Takao T, Nakata K, Fujisawa Y, Sasaki K, Watanabe K,Nakashima K, Urakami K, Ooya T, Takahashi M, Yuzuriha T, Serikawa K, Yoshimoto S,Nakagawa R, Kim JW, Ki CS, Won HH, Na DL, Seo SW, Mook-Jung I; Alzheimer Disease Genetics Consortium, St George-Hyslop P, Mayeux R, Haines JL, Pericak-Vance MA, Yoshida M, Nishida N, Tokunaga K, Yamamoto K, Tsuji S, Kanazawa I, Ihara Y, Schellenberg GD,Farrer LA, Kuwano R. PLoS One. 2013;8(4):e58618. |
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Critical role of presenilin-dependent ¥ã-secretase activity in DNA damage-induced promyelocytic leukemia protein expression and apoptosis. Song H, Boo JH, Kim KH, Kim C, Kim YE, Ahn JH, Jeon GS, Ryu H, Kang DE, Mook-Jung I. Cell Death Differ. 2013 Apr;20(4):639-48. |
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Amelioration of neurodegenerative diseases by cell death-induced cytoplasmic delivery of humanin. Park TY, Kim SH, Shin YC, Lee NH, Lee RK, Shim JH, Glimcher LH, Mook-Jung I, Cheong E,Kim WK, Honda F, Morio T, Lim JS, Lee SK.J Control Release. 2013 Mar 28;166(3):307-15. |
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A two-photon fluorescent probe for amyloid-¥â plaques in living mice. Heo CH, Kim KH, Kim HJ, Baik SH, Song H, Kim YS, Lee J, Mook-Jung I, Kim HM. Chem Commun (Camb). 2013 Feb 14;49(13):1303-5. |
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Vitamin D-binding protein interacts with A¥â and suppresses A¥â-mediated pathology. Moon M, Song H, Hong HJ, Nam DW, Cha MY, Oh MS, Yu J, Ryu H, Mook-Jung I. Cell Death Differ. 2013 Apr;20(4):630-8. |
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Effect of conjugated linoleic acid, ¥ì-calpain inhibitor, on pathogenesis of Alzheimer's disease. Lee E, Eom JE, Kim HL, Baek KH, Jun KY, Kim HJ, Lee M, Mook-Jung I, Kwon Y.Biochim Biophys Acta. 2013 Apr;1831(4):709-18. |
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Jin SM, Cho HJ, Kim YW, Hwang JY, Mook-Jung I. A¥â-induced Ca(2+) influx regulates astrocytic BACE1 expression via calcineurin/NFAT4 signals. Biochem Biophys Res Commun. 2012 Aug 31;425(3):649-55. |
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Son SM, Song H, Byun J, Park KS, Jang HC, Park YJ, Mook-Jung I. Accumulation of autophagosomes contributes to enhanced amyloidogenic APP processing under insulin-resistant conditions. Autophagy. 2012 Aug 29;8(12).
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