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2018

1. Regulation of autophagic proteolysis by the N-recognin SQSTM1/p62 of the N-end rule pathway.

Cha-Molstad H, Lee SH, Kim JG, Sung KW, Hwang J, Shim SM, Ganipisetti S, McGuire T, Mook-Jung I,  Ciechanover A, Xie XQ, Kim BY, Kwon YT.

Autophagy. 2018;14(2):359-361. doi: 10.1080/15548627.2017.1415190. Epub 2018 Jan 29.

 

2. Molecular and functional signatures in a novel Alzheimer's disease mouse model assessed by quantitative proteomics.

Kim DK, Park J, Han D, Yang J, Kim A, Woo J, Kim Y, Mook-Jung I.

Mol Neurodegener. 2018 Jan 16;13(1):2. doi: 10.1186/s13024-017-0234-4.

 

3. Visualization of Altered Hippocampal Connectivity in an Animal Model of Alzheimer's Disease.

Jeon SG, Kim YJ, Kim KA, Mook-Jung I, Moon M.

Mol Neurobiol. 2018 Oct;55(10):7886-7899. doi: 10.1007/s12035-018-0918-y. Epub 2018 Feb 27.

 

4. Thrombospondin-1 protects against Aβ-induced mitochondrial fragmentation and dysfunction in hippocampal cells.

Kang S, Byun J, Son SM, Mook-Jung I.

Cell Death Discov. 2018 Feb 20;4:31. doi: 10.1038/s41420-017-0023-4. eCollection 2018 Dec.

 

5. Intrahippocampal injection of a lentiviral vector expressing neurogranin enhances cognitive function in 5XFAD mice.

Jeon SG, Kang M, Kim YS, Kim DH, Nam DW, Song EJ, Mook-Jung I, Moon M.

Exp Mol Med. 2018 Mar 23;50(3):e461. doi: 10.1038/emm.2017.302.

 

6. O-GlcNAcylation regulates endoplasmic reticulum exit sites through Sec31A modification in conventional secretory pathway.

Cho HJ, Mook-Jung I. FASEB J. 2018 Sep;32(9):4641-4657. doi: 10.1096/fj.201701523R. Epub 2018 Apr 17.

 

7. Specific autophagy and ESCRT components participate in the unconventional secretion of CFTR.

Noh SH, Gee HY, Kim Y, Piao H, Kim J, Kang CM, Lee G, Mook-Jung I, Lee Y, Cho JW, Lee MG.

Autophagy. 2018;14(10):1761-1778. doi: 10.1080/15548627.2018.1489479. Epub 2018 Jul 31.

 

8. Blood acetylcholinesterase level is a potential biomarker for the early detection of cerebral amyloid deposition in cognitively normal individuals.

Han SH, Park JC, Byun MS, Yi D, Lee JH, Lee DY, Mook-Jung I; KBASE Research Group.

Neurobiol Aging. 2018 Sep 8;73:21-29. doi: 10.1016/j.neurobiolaging.2018.09.001. [Epub ahead of print]

 

9. SIRT3 deregulation is linked to mitochondrial dysfunction in Alzheimer's disease.  

Lee J, Kim Y, Liu T, Hwang YJ, Hyeon SJ, Im H, Lee K, Alvarez VE, McKee AC, Um SJ, Hur M, Mook-Jung I , Kowall NW, Ryu H. Aging Cell. 2018 Feb;17(1). doi: 10.1111/acel.12679. Epub 2017 Nov 11.

 

10.  Moderating effect of APOE ε4 on the relationship between sleep-wake cycle and brain β-amyloid.

Hwang JY, Byun MS, Choe YM, Lee JH, Yi D, Choi JW, Hwang SH, Lee YJ, Lee DY; KBASE Research Group. Neurology. 2018 Mar 27;90(13):e1167-e1173. doi: 10.1212/WNL.0000000000005193. Epub 2018 Feb 28.

 

11. Nurr1 (NR4A2) regulates Alzheimer's disease-related pathogenesis and cognitive function in the 5XFAD mouse model.

Moon M, Jung ES, Jeon SG, Cha MY, Jang Y, Kim W, Lopes C, Mook-Jung I,  Kim KS. Aging Cell. 2018 Dec 4:e12866. doi: 10.1111/acel.12866. [Epub ahead of print]

 

12. Amyloid β-induced elevation of O-GlcNAcylated c-Fos promotes neuronal cell death.

Choi H, Kim C, Song H, Cha MY, Cho HJ, Son SM, Kim HJ, Mook-Jung I.  Aging Cell. 2018 Dec 4:e12872. doi: 10.1111/acel.12872. [Epub ahead of print]

 


13. Plasma tau/amyloid-β1-42 ratio predicts brain tau deposition and neurodegeneration in Alzheimer's disease.
Park JC, Han SH, Yi D, Byun MS, Lee JH, Jang S, Ko K, Jeon SY, Lee YS, Kim YK, Lee DY, Mook-Jung I. Brain. 2019 Mar 1;142(3):771-786. doi: 10.1093/brain/awy347. 
 

14. Harnessing Intramolecular Rotation to Enhance Two-photon Imaging of Aβ Plaques Through Minimizing Background Fluorescence.
Shin J, Verwilst P, Choi H, Kang S, Han J, Kim NH, Choi JG, Oh MS, Hwang JS, Kim D, Mook-Jung I, Kim JS. Angew Chem Int Ed Engl. 2019 Feb 26. doi: 10.1002/anie.201900549. [Epub ahead of print]

 

 

 

 

Laboratory for Alzheimer's Disease Research,
#215 Biomedical Research Building, Seoul National University College of Medicine
28 Yeongeon-dong, Jongno-gu, Seoul 110-799, Korea. Tel) +82-2-3668-7636, Fax) +82-2-3672-7352