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2017

1. Cytosolic Extract of Human Adipose Stem Cells Reverses the Amyloid Beta-Induced Mitochondrial Apoptosis via P53/Foxo3a Pathway. Liu T, Lee M, Ban JJ, Im W, Mook-Jung I, Kim M.PLoS One. 2017 Jan 3;12(1):e0168859. doi: 10.1371/journal.pone.0168859.

2. Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease. Kim T, Yang HY, Park BG, Jung SY, Park JH, Park KD, Min SJ, Tae J, Yang H, Cho S, Cho SJ, Song H, Mook-Jung I, Lee J, Pae ANEur J Med Chem. 2017 Jan 5;125:1172-1192. doi: 10.1016/j.ejmech.2016.11.017.

3. Protein-Induced Pluripotent Stem Cells Ameliorate Cognitive Dysfunction and Reduce Aβ Deposition in a Mouse Model of Alzheimer's Disease. Cha MY, Kwon YW, Ahn HS, Jeong H, Lee YY, Moon M, Baik SH, Kim DK, Song H, Yi EC, Hwang D, Kim HS, Mook-Jung I.Stem Cells Transl Med. 2017 Jan;6(1):293-305. doi: 10.5966/sctm.2016-0081. 

4. PRAK mediates Aβ-RAGE driven autophagy pathway. Kim Y, Mook-Jung IOncotarget. 2017 Jan 24;8(4):5648-5649. doi: 10.18632/oncotarget.14544.

5. Annexin A1 restores Aβ1-42 -induced blood-brain barrier disruption through the inhibition of RhoA-ROCK signaling pathway. Park JC, Baik SH, Han SH, Cho HJ, Choi H, Kim HJ, Choi H, Lee W, Kim DK, Mook-Jung IAging Cell. 2017 Feb;16(1):149-161. doi: 10.1111/acel.12530.

6. Increased acetylation of Peroxiredoxin1 by HDAC6 inhibition leads to recovery of Aβ-induced impaired axonal transport. Choi H, Kim HJ, Kim J, Kim S, Yang J, Lee W, Park Y, Hyeon SJ, Lee DS, Ryu H, Chung J, Mook-Jung IMol Neurodegener. 2017 Feb 28;12(1):23. doi: 10.1186/s13024-017-0164-1.

7. Chemically treated plasma Aβ is a potential blood-based biomarker for screening cerebral amyloid deposition. Park JC, Han SH, Cho HJ, Byun MS, Yi D, Choe YM, Kang S, Jung ES, Won SJ, Kim EH, Kim YK, Lee DY, Mook-Jung IAlzheimers Res Ther. 2017 Mar 22;9(1):20. doi: 10.1186/s13195-017-0248-8.

8. p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis. Cha-Molstad H, Yu JE, Feng Z, Lee SH, Kim JG, Yang P, Han B, Sung KW, Yoo YD, Hwang J, McGuire T, Shim SM, Song HD, Ganipisetti S, Wang N, Jang JM, Lee MJ, Kim SJ, Lee KH, Hong JT, Ciechanover A, Mook-Jung I, Kim KP, Xie XQ, Kwon YT, Kim BY. Nat Commun. 2017 Jul 24;8(1):102. doi: 10.1038/s41467-017-00085-7.

9. TREM2 promotes Aβ phagocytosis by upregulating C/EBPα-dependent CD36 expression in microglia. Kim SM, Mun BR, Lee SJ, Joh Y, Lee HY, Ji KY, Choi HR, Lee EH, Kim EM, Jang JH, Song HW, Mook-Jung I, Choi WS, Kang HS. Sci Rep. 2017 Sep 11;7(1):11118. doi:10.1038/s41598-017-11634-x.

10. SIRT3 deregulation is linked to mitochondrial dysfunction in Alzheimer's disease. Lee J, Kim Y, Liu T, Hwang YJ, Hyeon SJ, Im H, Lee K, Alvarez VE, McKee AC, Um SJ, Hur M, Mook-Jung I, Kowall NW, Ryu H. Aging Cell. 2017 Nov 11. doi: 10.1111/acel.12679. [Epub ahead of print]

11. Low Serum Phosphorus Correlates with Cerebral Aβ Deposition in Cognitively Impaired Subjects: Results from the KBASE Study. Park JCHan SHByun MSYi DLee JHPark KLee DYMook-Jung I. Front Aging Neurosci. 2017 Nov 6;9:362. doi: 10.3389/fnagi.2017.00362. eCollection 2017.

 

12. Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's Disease: Methodology and Baseline Sample Characteristics. Byun MSYi DLee JHChoe YMSohn BKLee JYChoi HJBaek HKim YKLee YSSohn CHMook-Jung IChoi MLee YJLee DWRyu SHKim SGKim JWWoo JILee DYKBASE Research Group. Psychiatry Investig. 2017 Nov;14(6):851-863. doi: 10.4306/pi.2017.14.6.851. Epub 2017 Nov 7.

 

13. Mitochondrial abnormalities related to the dysfunction of circulating endothelial colony-forming cells in moyamoya disease. Choi JWSon SMMook-Jung IMoon YJLee JYWang KCKang HSPhi JHChoi SAChong SByun JKim SK. J Neurosurg. 2017 Dec 8:1-9. doi: 10.3171/2017.5.JNS17147. [Epub ahead of print]

 

Laboratory for Alzheimer's Disease Research,
#215 Biomedical Research Building, Seoul National University College of Medicine
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