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2014

1. Both targeted mass spectrometry and flow sorting analysis methods detected the decreased serum apolipoprotein e level in Alzheimer's disease patients. Han SH, Kim JS, Lee Y, Choi H, Kim JW, Na DL, Yang EG, Yu MH, Hwang D, Lee C, Mook-Jung I. Mol Cell Proteomics. Feb;13(2):407-19.

2. Migration of neutrophils targeting amyloid plaques in Alzheimer's disease mouse model. Baik SH, Cha MY, Hyun YM, Cho H, Hamza B, Kim DK, Han SH, Choi H, Kim KH, Moon M, Lee J, Kim M, Irimia D, Mook-Jung I. Neurobiol Aging. Jun;35(6):1286-92.

3. High-dose of vitamin C supplementation reduces amyloid plaque burden and ameliorates pathological changes in the brain of 5XFAD mice. Kook SY, Lee KM, Kim Y, Cha MY, Kang S, Baik SH, Lee H, Park R, Mook-Jung I. Cell Death Dis. Feb 27;5:e1083.

4. Impaired Hippocampal Neurogenesis and its Enhancement with Ghrelin in 5XFAD Mice. Moon M, Cha MY, Mook-Jung I. J Alzheimers Dis.  2014;41(1):233-41

5. Adenylyl cyclase-associated protein 1 is a receptor for human resistin and mediates inflammatory actions of human monocytes. Lee S, Lee HC, Kwon YW, Lee SE, Cho Y, Kim J, Lee S, Kim JY, Lee J, Yang HM, Mook-Jung I, Nam KY, Chung J, Lazar MA, Kim HS. Cell Metab. Mar 4;19(3):484-97.

6. Disruption of blood-brain barrier in Alzheimer disease pathogenesis. Kook SY, Seok Hong H, Moon M, Mook-Jung I. Tissue Barriers.  Apr 1;1(2):e23993.

7. CR6-interacting factor 1 is a key regulator in Aβ-induced mitochondrial disruption and pathogenesis of Alzheimer's disease. Byun J, Son SM, Cha MY, Shong M, Hwang YJ, Kim Y, Ryu H, Moon M, Kim KS, Mook-Jung I. Cell Death Differ. 2014 Nov 7. doi: 10.1038/cdd.2014.184. [Epub ahead of print]

8. Inhibition of Glutaminyl Cyclase Ameliorates Amyloid Pathology in an Animal Model of Alzheimer's Disease via the Modulation of γ-Secretase Activity. Song H, Chang YJ, Moon M, Park SK, Tran PT, Hoang VH, Lee J, Mook-Jung I. J Alzheimers Dis. 2014 Aug 11. [Epub ahead of print]

9. Diverse molecular targets for therapeutic strategies in Alzheimer's disease. Han SH, Mook-Jung I. J Korean Med Sci. 2014 Jul;29(7):893-902. doi: 10.3346/jkms.2014.29.7.893. Epub 2014 Jul 11.

10. Aβ1-42 reduces P-glycoprotein in the blood-brain barrier through RAGE-NF-κB signaling. Park R, Kook SY, Park JC, Mook-Jung I. Cell Death Dis. 2014 Jun 26;5:e1299. doi: 10.1038/cddis.2014.258.

11. Intracellular amyloid beta alters the tight junction of retinal pigment epithelium in 5XFAD mice. Park SW, Kim JH, Mook-Jung I, Kim KW, Park WJ, Park KH, Kim JH. Neurobiol Aging. 2014 Sep;35(9):2013-20. doi: 10.1016/j.neurobiolaging.2014.03.008. Epub 2014 Mar 15.

12. Reduced IRE1α mediates apoptotic cell death by disrupting calcium homeostasis via the InsP3 receptor. Son SM, Byun J, Roh SE, Kim SJ, Mook-Jung I. Cell Death Dis. 2014 Apr 17;5:e1188. doi: 10.1038/cddis.2014.129.

13. Phosphokinase antibody arrays on dendron-coated surface. Kwak JW, Jeong H, Han SH, Kim Y, Son SM, Mook-Jung I, Hwang D, Park JW. PLoS One. 2014 May 6;9(5):e96456. doi: 10.1371/journal.pone.0096456. eCollection 2014.

14. Modulation of mitochondrial function by stem cell-derived cellular components. Liu T, Im W, Lee ST, Ban JJ, Chai YJ, Lee M, Mook-Jung I, Chu K, Kim M. Biochem Biophys Res Commun. 2014 Jun 13;448(4):403-8. doi: 10.1016/j.bbrc.2014.04.129. Epub 2014 May 4.

15. Crucial role of calbindin-D28k in the pathogenesis of Alzheimer's disease mouse model. Kook SY, Jeong H, Kang MJ, Park R, Shin HJ, Han SH, Son SM, Song H, Baik SH, Moon M, Yi EC, Hwang D, Mook-Jung I. Cell Death Differ. 2014 Oct;21(10):1575-87. doi: 10.1038/cdd.2014.67. Epub 2014 May 23.

16. Amyloid beta-mediated epigenetic alteration of insulin-like growth factor binding protein 3 controls cell survival in Alzheimer's disease. Sung HY, Choi EN, Lyu D, Mook-Jung I, Ahn JH. PLoS One. 2014 Jun 25;9(6):e99047. doi: 10.1371/journal.pone.0099047. eCollection 2014.

 

 

 

Laboratory for Alzheimer's Disease Research,
#215 Biomedical Research Building, Seoul National University College of Medicine
28 Yeongeon-dong, Jongno-gu, Seoul 110-799, Korea. Tel) +82-2-3668-7636, Fax) +82-2-3672-7352