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153 TREM2 promotes Aβ phagocytosis by upregulating C/EBPα-dependent CD36 expression in microglia. Kim SM, Mun BR, Lee SJ, Joh Y, Lee HY, Ji KY, Choi HR, Lee EH, Kim EM, Jang JH, Song HW, Mook-Jung I, Choi WS, Kang HS. Sci Rep. 2017 Sep 11;7(1):11118. doi:10.1038/s41598-017-11634-x. Link
152 p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis. Cha-Molstad H, Yu JE, Feng Z, Lee SH, Kim JG, Yang P, Han B, Sung KW, Yoo YD, Hwang J, McGuire T, Shim SM, Song HD, Ganipisetti S, Wang N, Jang JM, Lee MJ, Kim SJ, Lee KH, Hong JT, Ciechanover A, Mook-Jung I, Kim KP, Xie XQ, Kwon YT, Kim BY. Nat Commun. 2017 Jul 24;8(1):102. doi: 10.1038/s41467-017-00085-7. Link
151 Chemically treated plasma Aβ is a potential blood-based biomarker for screening cerebral amyloid deposition. Park JC, Han SH, Cho HJ, Byun MS, Yi D, Choe YM, Kang S, Jung ES, Won SJ, Kim EH, Kim YK, Lee DY, Mook-Jung I. Alzheimers Res Ther. 2017 Mar 22;9(1):20. doi: 10.1186/s13195-017-0248-8. Link
150 Increased acetylation of Peroxiredoxin1 by HDAC6 inhibition leads to recovery of Aβ-induced impaired axonal transport. Choi H, Kim HJ, Kim J, Kim S, Yang J, Lee W, Park Y, Hyeon SJ, Lee DS, Ryu H, Chung J, Mook-Jung I. Mol Neurodegener. 2017 Feb 28;12(1):23. doi: 10.1186/s13024-017-0164-1. Link
149 Annexin A1 restores Aβ1-42 -induced blood-brain barrier disruption through the inhibition of RhoA-ROCK signaling pathway. Park JC, Baik SH, Han SH, Cho HJ, Choi H, Kim HJ, Choi H, Lee W, Kim DK, Mook-Jung I. Aging Cell. 2017 Feb;16(1):149-161. doi: 10.1111/acel.12530. Link
148 PRAK mediates Aβ-RAGE driven autophagy pathway. Kim Y, Mook-Jung I. Oncotarget. 2017 Jan 24;8(4):5648-5649. doi: 10.18632/oncotarget.14544. Link
147 Protein-Induced Pluripotent Stem Cells Ameliorate Cognitive Dysfunction and Reduce Aβ Deposition in a Mouse Model of Alzheimer's Disease. Cha MY, Kwon YW, Ahn HS, Jeong H, Lee YY, Moon M, Baik SH, Kim DK, Song H, Yi EC, Hwang D, Kim HS, Mook-Jung I.Stem Cells Transl Med. 2017 Jan;6(1):293-305. doi: 10.5966/sctm.2016-0081. Link
146 Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease. Kim T, Yang HY, Park BG, Jung SY, Park JH, Park KD, Min SJ, Tae J, Yang H, Cho S, Cho SJ, Song H, Mook-Jung I, Lee J, Pae AN. Eur J Med Chem. 2017 Jan 5;125:1172-1192. doi: 10.1016/j.ejmech.2016.11.017. Link
145 Cytosolic Extract of Human Adipose Stem Cells Reverses the Amyloid Beta-Induced Mitochondrial Apoptosis via P53/Foxo3a Pathway. Liu T, Lee M, Ban JJ, Im W, Mook-Jung I, Kim M.PLoS One. 2017 Jan 3;12(1):e0168859. doi: 10.1371/journal.pone.0168859. Link
144 HDAC6 Inhibitors Rescued the Defective Axonal Mitochondrial Movement in Motor Neurons Derived from the Induced Pluripotent Stem Cells of Peripheral Neuropathy Patients with HSPB1 Mutation. Kim JY, Woo SY, Hong YB, Choi H, Kim J, Choi H, Mook-Jung I, Ha N, Kyung J, Koo SK, Jung SC, Choi BO.Stem Cells Int. 2016;2016:9475981. doi: 10.1155/2016/9475981. Link